Dr. Chaiyen’s research interests are in the broad areas of enzyme catalysis, enzyme engineering, systems biocatalysis, metabolic engineering and synthetic biology. Her group studies flavin-dependent, PLP-dependent, redox and aldolase enzymes. They have contributed significantly to the understanding of many fundamental aspects of these systems including mechanisms of oxygen activation by flavoenzymes, reduced flavin transfer between proteins, oxygenation and oxidation by flavin-dependent enzymes. Their research contributes to applications in circular economy, green chemistry, white biotechnology, biofuels, biorefinery, biosensors and bioimaging. With the mission to translate their scientific discoveries into real applications, her group has collaborations with several private sector entities and also founded their own startups, Enzmart Biotech, in 2016 and BioSynThai Biotech in 2020.
Cash Return from ZeroWaste and Segregation of Trash
The main goal is to translate our deep understanding of enzymatic reactions into applied technology.
Our goal is to be one of the most prominent ventures in biotechnology academia.
Plant booster for Safe and Sustainable Agriculture
The nicotinamide biomimetic BNAH has been demonstrated to serve as an effective reductant for generating reduced flavin in the chemoenzymatic cascade reaction of bacterial luciferase.
The flavin‐dependent monooxygenase, HadA, catalyzes the dehalogenation and denitration of the toxicants, nitro‐ and halogenated phenols, to benzoquinone.
Enzymes that are capable of detoxifying halogenated phenols (HPs) and nitrophenols (NPs) are valuable for bioremediation and waste biorefining.