Chaiyen Research Group

Dr.Chaiyen's lab team focuses on developing deep insights into enzymatic mechanisms, discovering new enzymatic functions and re-routing of metabolic networks. The team also includes technology and engineering specialists who focus on prototype development, scaling up and implementation for real life usage.

About us

Dr. Chaiyen’s research interests are in the broad areas of enzyme catalysis, enzyme engineering, systems biocatalysis, metabolic engineering and synthetic biology. Her group studies flavin-dependent, PLP-dependent, redox and aldolase enzymes. They have contributed significantly to the understanding of many fundamental aspects of these systems including mechanisms of oxygen activation by flavoenzymes, reduced flavin transfer between proteins, oxygenation and oxidation by flavin-dependent enzymes. In addition to developing deep insights into enzymatic mechanisms, they also focus on discovering of new enzymatic functions and re-routing of metabolic networks. With the mission to translate their scientific discoveries into real applications, her group has collaborations with several private sector entities and also founded their own startups, Enzmart Biotech, in 2016 and BioSynThai Biotech in 2020.


Our technology and startup


Cash Return from ZeroWaste and Segregation of Trash


The main goal is to translate our deep understanding of enzymatic reactions into applied technology.


Our goal is to be one of the most prominent ventures in biotechnology academia.


Plant booster for Safe and Sustainable Agriculture

Highlighted Findings

Angew Chem
2022 Apr

Luciferin Synthesis and Pesticide Detection by Luminescence Enzymatic Cascades

Enzymatic reactions were developed to convert 19 phenolic derivatives containing halogen, nitro, and methyl substituents into eight D-luciferin analogues.

Chem Rev

Enzymes, In Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability

Since the industrial revolution, the rapid growth and development of global industries have depended largely upon the utilization of coal-derived chemicals, and more recently, the utilization of petroleum-based chemicals.